About acute intermittent porphyriaAcute intermittent porphyria is a rare genetic disease, result in the mutations in the PBGD gene in insufficient activity of a protein for the synthesis of heme. This leads to an accumulation of toxic intermediate metabolites to a host of problems, including acute, severe abdominal pain, psychiatric, neurological disorders and muscle weakness what. Long-term irreversible irreversible nerve damage, liver cancer and kidney failure mebeverine.org . Acute porphyric attacks can be life-threatening.
AIP affects 1 per 10,000 persons in the European Union.Currently available therapies do not prevent the symptoms and consequences of acute porphyric attacks. AMT has demonstrated that its product, AMT-021, results in normalization of the PBGD protein in an animal model of AIP. In this model, the treatment completely prevented the occurrence of attacks and significantly improved the neuropathy, untreated mice. AMT 021 is a long term normalization of PBGD provide protein acute acute porphyric attacks and their complications.
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