Frank van Gelder.

Cyril Moers, M How much does acyclovir 800 mg cost? .D., Jacqueline M. Smits, M.D., Ph.D., Mark-Hugo J. Maathuis, M.D., Ph.D.D., Frank van Gelder, Bogdan P. Napieralski, Margitta van Kasterop-Kutz, Jaap J. Homan van der Heide, M.D., Ph.D., Jean-Paul Squifflet, M.D., Ph.D., Ernest van Heurn, M.D., Ph.D. Kirste, M.D., Ph.D., Axel Rahmel, M.D., Ph.D., Henri G.D. Leuvenink, Ph.D., Andreas Paul, M.D., Ph.D., Jacques Pirenne, M.D., Ph.D., and Rutger J. Ploeg, M.D., Ph.D. In static cold storage, the kidney is flushed, cooled with one of several cold preservation solutions, and transported on ice.1 The normal deceased kidney donor today is older and has been subjected to more concomitant disease than donors were several decades ago; these factors may have a detrimental effect on allograft quality.2,3 Furthermore, the use of organs received from donors after cardiocirculatory death is increasing in most countries.4 Such allografts are recognized to have higher rates of delayed graft function significantly.4,5 Evidence suggests that organs that do not function soon after transplantation have an elevated risk of acute rejection, and allograft survival could be inferior.6,7 Furthermore, delayed graft function increases the costs of kidney transplantation.8,9 Retrospective research have suggested that machine perfusion could result in an improved short-term outcome, with lower rates of delayed graft function after transplantation of kidneys from all types of deceased donors.9-11 Therefore, interest in machine perfusion is increasing.